UQCRFS1

Across TCGA cell cohorts, UQCRFS1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UQCRFS1-associated genes across cancer lineages are SPEM3. Each is linked with UQCRFS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UQCRFS1-to-partner and partner-to-UQCRFS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPEM3 grouped by UQCRFS1-low versus UQCRFS1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRFS1→partner) and Y-score (partner→UQCRFS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPEM3 →	+0.016	+4.347	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SPEM3 by UQCRFS1 expression — LARGE_INTESTINE

Explore this box plot interactively →