UQCRC2

Across TCGA pan-cancer cohorts, UQCRC2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UQCRC2 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher UQCRC2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UQCRC2 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where UQCRC2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.912	.013	42	view →
CCRCC	DFS	Median	II,III,IV	0.979	0.163	.003	25	view →
PDAC	OS	Tertile	III,IV	0.191	0.669	.008	12	view →
HNSC	DFS	Tertile	III,IV	0.879	0.699	.015	10	view →
LUAD	OS	Tertile	All	0.656	0.910	.041	2	view →
GBM	OS	Median	All	0.879	0.751	.006	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UQCRC2–COAD (DFS)

Open the COAD breakdown →