UQCRC2

Across TCGA cell cohorts, UQCRC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,896 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible UQCRC2-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cell PML body, Quinone biosynthetic process, and Ubiquinone metabolic process. Each is linked with UQCRC2 in more than 12 cancer types. Because this analysis shows association rather than direction, both UQCRC2-to-partner and partner-to-UQCRC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cell PML body grouped by UQCRC2-low versus UQCRC2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRC2→partner) and Y-score (partner→UQCRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Symbiont-mediated disruption of host cell PML body →	+0.090	+0.810	<.001	<.001	3	13
BREAST	Quinone biosynthetic process →	+0.090	+0.734	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Ubiquinone metabolic process →	+0.081	+0.546	<.001	<.001	3	10
BREAST	Ubiquinone biosynthetic process →	+0.090	+0.734	<.001	<.001	3	10
LARGE_INTESTINE	Mitochondrial ribosome assembly →	+0.070	+0.641	<.001	<.001	3	10
PANCREAS	Pyruvate decarboxylation to acetyl-CoA →	+0.129	+0.624	.005	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,896 associations by consensus.

Symbiont-mediated disruption of host cell PML body by UQCRC2 expression — PANCREAS

Explore this box plot interactively →