UQCRB

Across TCGA patient cohorts, UQCRB protein abundance is significantly associated with the RNA expression of many other genes, with 10,423 significant associations in total. COAD shows the largest number of these associations.

The most reproducible UQCRB-associated genes across cancer lineages are NEXN, PMP22, and CNRIP1. Each is linked with UQCRB in more than 5 cancer types. Because this analysis shows association rather than direction, both UQCRB-to-partner and partner-to-UQCRB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UQCRB versus NEXN in UCEC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRB→partner) and Y-score (partner→UQCRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NEXN →	-0.906	-0.362	.001	.002	3	6
OV	PMP22 →	-0.686	-0.393	<.001	<.001	3	5
UCEC	CNRIP1 →	-0.946	-0.444	<.001	<.001	3	5
OV	GLT8D2 →	-0.886	-0.462	.008	.004	3	5
OV	BICC1 →	-1.009	-0.538	<.001	<.001	3	5
UCEC	TRPC1 →	-0.927	-0.367	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,423 associations by consensus.

UQCRB vs NEXN — UCEC

Explore this scatter interactively →