UQCRB

Across TCGA patient cohorts, UQCRB mutation is significantly associated with the RNA expression of many other genes, with 409 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UQCRB-associated genes across cancer lineages are KRTAP19-7, SNRPGP17, and MIR6864. Each is linked with UQCRB in more than 1 cancer types. Because this analysis shows association rather than direction, both UQCRB-to-partner and partner-to-UQCRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-7 grouped by UQCRB-low versus UQCRB-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRB→partner) and Y-score (partner→UQCRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KRTAP19-7 →	+0.148	+7.741	<.001	.009	3	2
UCEC	SNRPGP17 →	+0.468	+4.048	<.001	<.001	3	1
UCEC	MIR6864 →	+0.805	+2.546	<.001	.004	3	1
UCEC	RN7SL650P →	+0.400	+2.581	<.001	.006	3	1
UCEC	H2AC12 →	+0.665	+3.343	.007	.005	3	1
UCEC	RPS29P32 →	+0.517	+2.792	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 409 associations by consensus.

KRTAP19-7 by UQCRB expression — COAD

Explore this box plot interactively →