UQCRB

Across TCGA cell cohorts, UQCRB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,772 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UQCRB-associated GO terms across cancer lineages are Blastocyst growth, Mitochondrial respiratory chain complex assembly, and Negative regulation of protein localization to centrosome. Each is linked with UQCRB in more than 10 cancer types. Because this analysis shows association rather than direction, both UQCRB-to-partner and partner-to-UQCRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blastocyst growth grouped by UQCRB-low versus UQCRB-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRB→partner) and Y-score (partner→UQCRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Blastocyst growth →	+0.215	+0.800	<.001	.007	3	11
LARGE_INTESTINE	Mitochondrial respiratory chain complex assembly →	+0.047	+0.498	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Negative regulation of protein localization to centrosome →	+0.173	+0.990	.002	.004	3	9
UPPER_AERODIGESTIVE_TRACT	Cell junction assembly →	-0.049	-0.595	.001	<.001	3	8
LARGE_INTESTINE	NADH dehydrogenase complex assembly →	+0.068	+0.580	<.001	.001	3	8
LARGE_INTESTINE	Mitochondrial respiratory chain complex I assembly →	+0.068	+0.580	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,772 associations by consensus.

Blastocyst growth by UQCRB expression — LIVER

Explore this box plot interactively →