UQCR11

Across TCGA patient cohorts, UQCR11 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UQCR11-associated genes across cancer lineages are MIR4804, RNA5SP327, and RNU6-662P. Each is linked with UQCR11 in more than 1 cancer types. Because this analysis shows association rather than direction, both UQCR11-to-partner and partner-to-UQCR11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4804 grouped by UQCR11-low versus UQCR11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCR11→partner) and Y-score (partner→UQCR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4804 →	+1.297	+5.133	<.001	.008	3	1
UCEC	RNA5SP327 →	+0.741	+5.420	<.001	.005	3	1
UCEC	RNU6-662P →	+1.081	+5.299	<.001	.006	3	1
UCEC	RNA5SP303 →	+0.673	+5.358	<.001	.006	3	1
UCEC	RNU6-927P →	+0.741	+5.242	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MIR4804 by UQCR11 expression — UCEC

Explore this box plot interactively →