UQCC2

Across TCGA pan-cancer cohorts, UQCC2 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated UQCC2 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher UQCC2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UQCC2 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, CCRCC, and LSCC are the cancer types where UQCC2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.918	.012	36	view →
CCRCC	OS	Tertile	All	0.753	0.942	.017	17	view →
LSCC	OS	Median	II,III,IV	0.874	0.662	.010	8	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.306	.010	6	view →
GBM	OS	Quartile	All	0.540	0.328	.038	2	view →
HNSC	DFS	Median	II,III,IV	0.904	0.984	.028	2	view →
PDAC	OS	Median	All	0.597	0.482	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

UQCC2–COAD (DFS)

Open the COAD breakdown →