UQCC2

Across TCGA patient cohorts, UQCC2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LGG shows the largest number of these associations.

The most reproducible UQCC2-associated genes across cancer lineages are MIR557 and RNU4ATAC10P. Each is linked with UQCC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UQCC2-to-partner and partner-to-UQCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR557 grouped by UQCC2-low versus UQCC2-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCC2→partner) and Y-score (partner→UQCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	MIR557 →	+0.348	+7.977	<.001	.007	3	1
LGG	RNU4ATAC10P →	+0.294	+7.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MIR557 by UQCC2 expression — LGG

Explore this box plot interactively →