Across TCGA patient cohorts, UPP1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,975 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UPP1-associated genes across cancer lineages are LILRB1, CD86, and TREM1. Each is linked with UPP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both UPP1-to-partner and partner-to-UPP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UPP1→partner) and Y-score (partner→UPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LILRB1 →	+0.708	+0.761	<.001	<.001	3	9
OV	CD86 →	+0.978	+0.595	<.001	<.001	3	9
GBM	TREM1 →	+1.209	+0.710	<.001	<.001	3	9
GBM	MYO1G →	+0.839	+0.831	<.001	<.001	3	9
OV	FCER1G →	+1.307	+0.940	<.001	<.001	3	9
OV	CCR1 →	+1.003	+0.551	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,975 associations by consensus.

Exploration

UPP1 survival (RNA) · tumor vs normal (RNA) · all UPP1 data types