Across TCGA cell cohorts, UPP1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,547 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UPP1-associated genes across cancer lineages are FOSL1, C7orf57, and TNFRSF12A. Each is linked with UPP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both UPP1-to-partner and partner-to-UPP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UPP1→partner) and Y-score (partner→UPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	FOSL1 →	+3.998	+2.353	<.001	<.001	3	14
CNS	C7orf57 →	+0.814	+1.486	<.001	<.001	3	11
BONE	TNFRSF12A →	+3.550	+2.593	<.001	<.001	3	11
OESOPHAGUS	H3-3A →	-0.998	-2.209	<.001	<.001	3	10
STOMACH	ZFAND2A →	+1.065	+2.562	<.001	<.001	2	11
BONE	MAFF →	+1.702	+2.796	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,547 associations by consensus.

Exploration

UPP1 survival (RNA) · tumor vs normal (RNA) · all UPP1 data types