Across TCGA cell cohorts, UPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,656 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible UPP1-associated GO terms across cancer lineages are Uridine metabolic process, Pyrimidine ribonucleoside metabolic process, and Pyrimidine nucleoside catabolic process. Each is linked with UPP1 in more than 19 cancer types. Because this analysis shows association rather than direction, both UPP1-to-partner and partner-to-UPP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UPP1→partner) and Y-score (partner→UPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Uridine metabolic process →	+1.876	+3.309	<.001	<.001	3	20
BONE	Pyrimidine ribonucleoside metabolic process →	+1.876	+3.309	<.001	<.001	3	20
LUNG_SCLC	Pyrimidine nucleoside catabolic process →	+1.784	+2.773	<.001	<.001	3	20
OESOPHAGUS	DTMP catabolic process →	+0.297	+2.625	<.001	.001	3	19
STOMACH	UMP catabolic process →	+0.301	+2.401	<.001	.003	3	18
STOMACH	DUMP catabolic process →	+0.301	+2.401	<.001	.003	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,656 associations by consensus.

Exploration

UPP1 survival (RNA) · tumor vs normal (RNA) · all UPP1 data types