UPK3BP1

Across TCGA pan-cancer cohorts, UPK3BP1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated UPK3BP1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher UPK3BP1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated UPK3BP1 expression acts as an unfavorable survival marker, although some lineages such as STAD and LUSC show a favorable association.

STAD, KIRP, and PAAD are the cancer types where UPK3BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	III,IV	0.650	0.330	.009	31	view →
KIRP	DFS	Tertile	All	0.842	0.959	.001	28	view →
PAAD	OS	Tertile	All	0.488	0.784	.002	27	view →
LUSC	OS	Tertile	III,IV	0.693	0.360	.004	15	view →
LGG	OS	Quartile	All	0.837	0.913	.002	15	view →
SKCM	DFS	Median	IV	0.729	0.155	.007	12	view →
KIRC	DFS	Quartile	All	0.494	0.674	.013	11	view →
THCA	DFS	Median	II,III,IV	0.663	0.873	.022	9	view →
COAD	DFS	Tertile	II,III,IV	0.872	0.693	.003	8	view →
PRAD	DFS	Median	All	0.906	0.959	.014	8	view →
READ	DFS	Quartile	III,IV	0.827	0.297	.033	7	view →
HNSC	DFS	Quartile	All	0.793	0.675	.030	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

UPK3BP1–STAD (OS)

Open the STAD breakdown →