UPK3BP1

Across TCGA pan-cancer cohorts, UPK3BP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of UPK3BP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where UPK3BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UPK3BP1 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

KIRP, KIRC, and STAD are the cancer types where UPK3BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UPK3BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	+0.102	<.001	7	view →
KIRC	All	All	+0.101	<.001	7	view →
STAD	All	All	+0.476	.002	4	view →
BRCA	All	All	+0.123	.004	4	view →
BLCA	Male	IV	+0.440	.006	2	view →
LUSC	Male	All	+0.192	.010	2	view →
LUAD	Male	III,IV	−0.408	<.001	1	view →
LIHC	All	All	+0.072	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

UPK3BP1–KIRP

Open the KIRP breakdown →