UPK3B

Across TCGA cell cohorts, UPK3B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,962 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UPK3B-associated GO terms across cancer lineages are Regulation of ruffle assembly, Hemidesmosome assembly, and Cell-substrate junction assembly. Each is linked with UPK3B in more than 10 cancer types. Because this analysis shows association rather than direction, both UPK3B-to-partner and partner-to-UPK3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ruffle assembly grouped by UPK3B-low versus UPK3B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UPK3B→partner) and Y-score (partner→UPK3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of ruffle assembly →	+0.217	+3.356	.003	<.001	3	11
BONE	Hemidesmosome assembly →	+0.355	+0.270	.002	.001	3	11
LARGE_INTESTINE	Cell-substrate junction assembly →	+0.168	+1.928	<.001	<.001	3	11
URINARY_TRACT	Negative regulation of hippocampal neuron apoptotic process →	+1.395	+3.113	<.001	<.001	3	11
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.083	+3.524	.001	<.001	3	10
BONE	Positive regulation of ruffle assembly →	+0.174	+0.256	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,962 associations by consensus.

Regulation of ruffle assembly by UPK3B expression — OESOPHAGUS

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