UPK3A

Across TCGA patient cohorts, UPK3A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,154 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible UPK3A-associated GO terms across cancer lineages are Peroxisome fission, Oxidative phosphorylation, and Proton motive force-driven ATP synthesis. Each is linked with UPK3A in more than 16 cancer types. Because this analysis shows association rather than direction, both UPK3A-to-partner and partner-to-UPK3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peroxisome fission grouped by UPK3A-low versus UPK3A-high in BLCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UPK3A→partner) and Y-score (partner→UPK3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Peroxisome fission →	+0.050	+3.244	<.001	<.001	3	17
STAD	Oxidative phosphorylation →	+0.054	+0.882	<.001	<.001	3	17
STAD	Proton motive force-driven ATP synthesis →	+0.051	+0.641	<.001	.007	1	17
ESCA	Galactose catabolic process →	+0.078	+1.238	<.001	<.001	3	15
LAML	Positive regulation of monocyte differentiation →	+0.100	+1.059	<.001	<.001	3	15
ESCA	Response to phorbol 13-acetate 12-myristate →	+0.065	+0.840	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,154 associations by consensus.

Peroxisome fission by UPK3A expression — BLCA

Explore this box plot interactively →