UPK1A

Across TCGA patient cohorts, UPK1A protein abundance is significantly associated with the RNA expression of many other genes, with 2,505 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UPK1A-associated genes across cancer lineages are SCIN, SEMA6A, and RAB41. Each is linked with UPK1A in more than 2 cancer types. Because this analysis shows association rather than direction, both UPK1A-to-partner and partner-to-UPK1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UPK1A versus SCIN in LUAD, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UPK1A→partner) and Y-score (partner→UPK1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SCIN →	+3.383	+1.248	<.001	.002	3	3
GBM	SEMA6A →	-0.605	-0.341	.001	<.001	3	2
BRCA	RAB41 →	-0.459	-0.753	.001	.003	3	2
BRCA	TCTEX1D2 →	-1.366	-0.753	.005	.003	3	2
CCRCC	WDR13 →	-0.551	-0.405	.001	<.001	3	2
GBM	ACTG1P1 →	-0.717	-0.391	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,505 associations by consensus.

UPK1A vs SCIN — LUAD

Explore this scatter interactively →