UPF3A

Across TCGA cell cohorts, UPF3A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,461 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UPF3A-associated GO terms across cancer lineages are Positive regulation of DNA repair, Ribosomal protein import into nucleus, and Microtubule nucleation. Each is linked with UPF3A in more than 14 cancer types. Because this analysis shows association rather than direction, both UPF3A-to-partner and partner-to-UPF3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by UPF3A-low versus UPF3A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UPF3A→partner) and Y-score (partner→UPF3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of DNA repair →	+0.061	+0.812	.001	<.001	3	15
OESOPHAGUS	Ribosomal protein import into nucleus →	+0.116	+0.846	.001	.003	3	15
SOFT_TISSUE	Microtubule nucleation →	+0.132	+0.881	<.001	<.001	3	14
PANCREAS	Positive regulation of DNA metabolic process →	+0.059	+1.036	.001	<.001	3	13
LUNG_SCLC	Centrosome duplication →	+0.123	+1.042	<.001	<.001	3	13
SOFT_TISSUE	Viral translational termination-reinitiation →	+0.085	+0.829	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,461 associations by consensus.

Positive regulation of DNA repair by UPF3A expression — STOMACH

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