UPB1

Across TCGA patient cohorts, UPB1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,418 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UPB1-associated genes across cancer lineages are SEPTIN3, KDELR3, and SUN2. Each is linked with UPB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UPB1-to-partner and partner-to-UPB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UPB1 versus SEPTIN3 in CCRCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UPB1→partner) and Y-score (partner→UPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEPTIN3 →	-0.598	-0.663	<.001	<.001	3	1
CCRCC	KDELR3 →	-0.916	-0.644	<.001	<.001	3	1
CCRCC	SUN2 →	+0.325	+0.617	.003	<.001	3	1
CCRCC	C22orf31 →	+0.345	+0.616	.001	<.001	3	1
CCRCC	KIAA0930 →	-0.431	-0.473	.001	.007	3	1
CCRCC	KCTD17 →	-0.370	-0.566	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,418 associations by consensus.

UPB1 vs SEPTIN3 — CCRCC

Explore this scatter interactively →