UNG

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UNG protein abundance is significantly associated with the RNA expression of many other genes, with 17,966 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UNG-associated genes across cancer lineages are TSHZ3, ZEB2, and TCEAL7. Each is linked with UNG in more than 6 cancer types. Because this analysis shows association rather than direction, both UNG-to-partner and partner-to-UNG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNG versus TSHZ3 in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNG→partner) and Y-score (partner→UNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTSHZ3 →-1.094-0.359<.001<.00137
OVZEB2 →-0.840-0.445<.001<.00137
UCECTCEAL7 →-1.181-0.299<.001.00137
LUADBRI3BP →+0.710+0.530<.001<.00137
LSCCCAV1 →-1.177-0.588<.001<.00137
LSCCRIPOR2 →-1.141-0.744<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,966 associations by consensus.

UNG vs TSHZ3 — UCEC

Per-sample scatter of UNG vs TSHZ3 in UCEC (Pearson r = -0.40).

Explore this scatter interactively →

Exploration