UNC93B3

Across TCGA patient cohorts, UNC93B3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,701 significant associations in total. THYM shows the largest number of these associations.

The most reproducible UNC93B3-associated GO terms across cancer lineages are Heparan sulfate proteoglycan catabolic process, ATP biosynthetic process, and Protein insertion into ER membrane. Each is linked with UNC93B3 in more than 15 cancer types. Because this analysis shows association rather than direction, both UNC93B3-to-partner and partner-to-UNC93B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heparan sulfate proteoglycan catabolic process grouped by UNC93B3-low versus UNC93B3-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93B3→partner) and Y-score (partner→UNC93B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Heparan sulfate proteoglycan catabolic process →	+0.058	+0.344	<.001	.002	3	16
PAAD	ATP biosynthetic process →	+0.026	+0.383	<.001	<.001	3	11
THYM	Protein insertion into ER membrane →	+0.039	+1.038	<.001	<.001	3	10
PAAD	Nucleoside triphosphate biosynthetic process →	+0.026	+0.387	<.001	<.001	3	10
ESCA	Glycerolipid biosynthetic process →	+0.055	+0.346	<.001	<.001	3	10
PAAD	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.035	+0.359	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,701 associations by consensus.

Heparan sulfate proteoglycan catabolic process by UNC93B3 expression — GBM

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