UNC93B1

Across TCGA patient cohorts, UNC93B1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,869 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UNC93B1-associated genes across cancer lineages are FBXO6, ISG20, and CASKIN2. Each is linked with UNC93B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both UNC93B1-to-partner and partner-to-UNC93B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC93B1 versus FBXO6 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93B1→partner) and Y-score (partner→UNC93B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FBXO6 →	+0.838	+0.831	<.001	<.001	3	6
HNSC	ISG20 →	+0.771	+0.336	.001	.006	3	5
CCRCC	CASKIN2 →	-0.519	-0.331	<.001	<.001	3	5
HNSC	P2RY10 →	+1.124	+0.376	<.001	<.001	3	5
GBM	SQOR →	+0.823	+0.414	<.001	<.001	3	5
BRCA	UBE2L6 →	+1.056	+0.760	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,869 associations by consensus.

UNC93B1 vs FBXO6 — OV

Explore this scatter interactively →