UNC93B1

Across TCGA patient cohorts, UNC93B1 mutation is significantly associated with the RNA expression of many other genes, with 940 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UNC93B1-associated genes across cancer lineages are RNU6-994P, OR51P1P, and RNA5SP484. Each is linked with UNC93B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC93B1-to-partner and partner-to-UNC93B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-994P grouped by UNC93B1-low versus UNC93B1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93B1→partner) and Y-score (partner→UNC93B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-994P →	+0.493	+7.640	<.001	.009	3	1
BLCA	OR51P1P →	+0.039	+7.640	<.001	.009	3	1
BLCA	RNA5SP484 →	+0.493	+7.640	<.001	.009	3	1
UCEC	ARF4P1 →	+0.510	+2.321	<.001	.006	3	1
UCEC	DGCR11 →	+0.452	+3.000	.004	.001	3	1
UCEC	CYFIP1 →	+0.617	+3.032	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 940 associations by consensus.

RNU6-994P by UNC93B1 expression — BLCA

Explore this box plot interactively →