UNC93B1

Across TCGA cell cohorts, UNC93B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,000 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UNC93B1-associated GO terms across cancer lineages are Toll-like receptor 7 signaling pathway, Protein localization to cell periphery, and Plasma membrane organization. Each is linked with UNC93B1 in more than 19 cancer types. Because this analysis shows association rather than direction, both UNC93B1-to-partner and partner-to-UNC93B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Toll-like receptor 7 signaling pathway grouped by UNC93B1-low versus UNC93B1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93B1→partner) and Y-score (partner→UNC93B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Toll-like receptor 7 signaling pathway →	+1.506	+2.262	<.001	<.001	3	20
BONE	Protein localization to cell periphery →	+0.069	+1.817	<.001	<.001	3	13
BONE	Plasma membrane organization →	+0.149	+1.646	<.001	<.001	3	13
LUNG_SCLC	Response to ketone →	+0.069	+1.576	<.001	.001	3	13
BONE	Regulation of protein localization to cell periphery →	+0.089	+2.024	<.001	<.001	3	12
SOFT_TISSUE	Toll-like receptor 3 signaling pathway →	+0.128	+1.978	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,000 associations by consensus.

Toll-like receptor 7 signaling pathway by UNC93B1 expression — LUNG_SCLC

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