UNC93B1

Across TCGA cell cohorts, UNC93B1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UNC93B1-associated genes across cancer lineages are DCANP1, OR4D11, and OR4N2. Each is linked with UNC93B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC93B1-to-partner and partner-to-UNC93B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCANP1 grouped by UNC93B1-low versus UNC93B1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93B1→partner) and Y-score (partner→UNC93B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DCANP1 →	+0.011	+4.467	<.001	.004	3	2
SKIN	OR4D11 →	+0.032	+5.022	<.001	.002	3	1
BLOOD_Lymphoma	OR4N2 →	+0.012	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	SCGB1C1 →	+0.101	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	SPANXN2 →	+0.149	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	MYH13 →	+0.021	+4.191	.009	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

DCANP1 by UNC93B1 expression — SKIN

Explore this box plot interactively →