UNC93A

Across TCGA patient cohorts, UNC93A mutation is significantly associated with the RNA expression of many other genes, with 3,370 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UNC93A-associated genes across cancer lineages are MTATP6P21, DNAJC9, and RNU6-838P. Each is linked with UNC93A in more than 2 cancer types. Because this analysis shows association rather than direction, both UNC93A-to-partner and partner-to-UNC93A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTATP6P21 grouped by UNC93A-low versus UNC93A-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93A→partner) and Y-score (partner→UNC93A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MTATP6P21 →	+0.117	+4.272	<.001	.005	3	3
UCEC	DNAJC9 →	+0.539	+2.592	.002	<.001	3	3
HNSC	RNU6-838P →	+0.324	+6.008	<.001	.002	3	2
SKCM	RNA5SP249 →	+0.048	+3.836	<.001	.007	3	2
SKCM	RNU6-542P →	+0.138	+3.376	<.001	<.001	3	2
HNSC	RPL23AP33 →	+0.107	+6.608	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,370 associations by consensus.

MTATP6P21 by UNC93A expression — LUSC

Explore this box plot interactively →