UNC93A

Across TCGA pan-cancer cohorts, UNC93A RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated UNC93A data layer compared with 8 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher UNC93A RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UNC93A expression acts as an unfavorable survival marker, although some lineages such as ESCA and THYM show a favorable association.

KICH, BRCA, and SKCM are the cancer types where UNC93A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.384	0.872	<.001	114	view →
BRCA	OS	Tertile	II,III,IV	0.867	0.940	<.001	62	view →
SKCM	OS	Quartile	All	0.169	0.363	<.001	49	view →
BLCA	OS	Tertile	IV	0.162	0.372	.004	34	view →
ESCA	OS	Median	III,IV	0.699	0.440	.007	29	view →
COAD	OS	Median	II,III,IV	0.768	0.941	<.001	29	view →
DLBC	OS	Tertile	All	0.419	0.949	.007	24	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	24	view →
THYM	DFS	Tertile	II,III,IV	1.000	0.551	.010	23	view →
TGCT	DFS	Tertile	All	0.581	0.876	.004	18	view →
UVM	DFS	Tertile	All	0.141	0.744	.024	18	view →
PRAD	DFS	Tertile	All	0.894	0.738	.019	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

UNC93A–KICH (DFS)

Open the KICH breakdown →