UNC93A

Across TCGA cell cohorts, UNC93A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,114 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UNC93A-associated GO terms across cancer lineages are Positive regulation of gastrulation, Cytotoxic T cell degranulation, and Ephrin receptor signaling pathway. Each is linked with UNC93A in more than 3 cancer types. Because this analysis shows association rather than direction, both UNC93A-to-partner and partner-to-UNC93A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of gastrulation grouped by UNC93A-low versus UNC93A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93A→partner) and Y-score (partner→UNC93A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of gastrulation →	-0.169	-1.645	<.001	<.001	3	4
LARGE_INTESTINE	Cytotoxic T cell degranulation →	+0.180	+1.704	<.001	<.001	3	4
LIVER	Ephrin receptor signaling pathway →	+0.103	+2.340	.008	.007	3	4
LARGE_INTESTINE	Regulation of membrane lipid distribution →	+0.070	+1.479	<.001	<.001	3	3
LUNG_SCLC	Response to anisomycin →	+0.166	+0.306	.002	.002	2	4
BLOOD_Leukemia	Negative regulation of cardiac muscle tissue growth →	+0.082	+0.024	<.001	.006	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,114 associations by consensus.

Positive regulation of gastrulation by UNC93A expression — LARGE_INTESTINE

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