UNC79

Across TCGA pan-cancer cohorts, UNC79 Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated UNC79 data layer compared with 21 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher UNC79 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated UNC79 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

KIRP, BLCA, and PCPG are the cancer types where UNC79 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.040	0.912	<.001	36	view →
BLCA	OS	Median	All	0.169	0.596	.018	12	view →
PCPG	DFS	Median	All	0.025	0.936	<.001	6	view →
STAD	OS	Median	III,IV	0.258	0.647	.027	6	view →
UCEC	DFS	Median	All	0.886	0.609	.011	6	view →
SKCM	DFS	Median	III,IV	0.397	0.670	.038	4	view →
SARC	DFS	Median	All	0.065	0.632	<.001	3	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
LUAD	OS	Median	All	0.794	0.671	.043	3	view →
LIHC	DFS	Median	All	0.183	0.532	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

UNC79–KIRP (DFS)

Open the KIRP breakdown →