UNC79

Across TCGA pan-cancer cohorts, UNC79 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of UNC79’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where UNC79 RNA is repressed in tumor relative to normal tissue. In most cancer types UNC79 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and ESCA are the cancer types where UNC79 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UNC79 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	−0.153	<.001	11	view →
KICH	All	II,III,IV	−0.282	<.001	10	view →
ESCA	All	All	−0.360	<.001	5	view →
THCA	Male	II,III,IV	−0.165	.004	4	view →
READ	All	All	−0.171	.001	2	view →
LUSC	All	All	+0.126	.010	2	view →
LUAD	Female	All	−0.085	.011	2	view →
KIRP	Female	All	+0.467	.049	1	view →
STAD	Male	All	−0.114	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

UNC79–COAD

Open the COAD breakdown →