UNC79

Across TCGA patient cohorts, UNC79 mutation is significantly associated with the RNA expression of many other genes, with 7,751 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UNC79-associated genes across cancer lineages are SNRPD3, ZWINT, and RPL23AP7. Each is linked with UNC79 in more than 5 cancer types. Because this analysis shows association rather than direction, both UNC79-to-partner and partner-to-UNC79 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPD3 grouped by UNC79-low versus UNC79-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC79→partner) and Y-score (partner→UNC79) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPD3 →	+0.296	+1.523	<.001	<.001	3	6
STAD	ZWINT →	+0.692	+2.832	<.001	.001	3	6
UCEC	RPL23AP7 →	+0.364	+2.465	<.001	<.001	3	6
STAD	PBK →	+1.015	+2.016	<.001	.005	3	6
SKCM	C19orf48 →	+0.319	+1.179	<.001	.001	3	6
UCEC	RPL23AP82 →	+0.421	+1.300	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,751 associations by consensus.

SNRPD3 by UNC79 expression — UCEC

Explore this box plot interactively →