UNC5D

Across TCGA cell cohorts, UNC5D RNA expression is significantly associated with the go_rna of many other GO terms, with 267 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible UNC5D-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with UNC5D in more than 5 cancer types. Because this analysis shows association rather than direction, both UNC5D-to-partner and partner-to-UNC5D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by UNC5D-low versus UNC5D-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC5D→partner) and Y-score (partner→UNC5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.120	+0.024	.001	.004	2	6
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.121	+0.024	.001	.004	2	6
STOMACH	Regulation of myoblast fusion →	+0.104	+0.024	.002	.004	1	6
BONE	Positive regulation of monoatomic ion transport →	-0.089	-0.687	.004	.009	2	5
LUNG_SCLC	snRNA processing →	+0.057	+0.796	<.001	.005	3	4
LUNG_SCLC	mRNA export from nucleus →	+0.092	+0.772	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 267 associations by consensus.

Negative regulation of myoblast fusion by UNC5D expression — STOMACH

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