UNC5CL

Across TCGA patient cohorts, UNC5CL protein abundance is significantly associated with the RNA expression of many other genes, with 5,080 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible UNC5CL-associated genes across cancer lineages are HMGN2P21, PPM1F, and TAB1. Each is linked with UNC5CL in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC5CL-to-partner and partner-to-UNC5CL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC5CL versus HMGN2P21 in HNSC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC5CL→partner) and Y-score (partner→UNC5CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HMGN2P21 →	+1.900	+0.813	.002	.009	3	2
PDAC	PPM1F →	-0.329	-0.932	.001	<.001	3	1
PDAC	TAB1 →	-0.409	-0.847	.002	.002	3	1
PDAC	ZC3H7B →	-0.404	-0.912	.001	.001	3	1
PDAC	PYGL →	-0.762	-0.879	<.001	<.001	3	1
PDAC	ASB2 →	-0.486	-0.672	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,080 associations by consensus.

UNC5CL vs HMGN2P21 — HNSC

Explore this scatter interactively →