UNC5CL

Across TCGA patient cohorts, UNC5CL protein abundance is significantly associated with the protein abundance of many other proteins, with 11,538 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible UNC5CL-associated proteins across cancer lineages are GPHN_S305, RABGAP1_S56, and TPRN_S364. Each is linked with UNC5CL in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC5CL-to-partner and partner-to-UNC5CL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC5CL versus GPHN_S305 in CCRCC, with a Pearson correlation of 0.29.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC5CL→partner) and Y-score (partner→UNC5CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GPHN_S305 →	+0.581	+0.341	.001	.002	3	2
PDAC	RABGAP1_S56 →	+0.822	+1.188	<.001	<.001	3	2
CCRCC	TPRN_S364 →	+0.690	+0.489	<.001	.001	3	2
CCRCC	LLGL1_S1044 →	+0.920	+0.566	<.001	<.001	3	2
CCRCC	PTPRK →	+0.305	+0.409	<.001	.001	3	2
HNSC	YBX3_S346 →	-1.003	-0.601	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,538 associations by consensus.

UNC5CL vs GPHN_S305 — CCRCC

Explore this scatter interactively →