UNC5B

Across TCGA cell cohorts, UNC5B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,586 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UNC5B-associated GO terms across cancer lineages are Anterior/posterior axon guidance, Regulation of syncytium formation by plasma membrane fusion, and Response to endoplasmic reticulum stress. Each is linked with UNC5B in more than 14 cancer types. Because this analysis shows association rather than direction, both UNC5B-to-partner and partner-to-UNC5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anterior/posterior axon guidance grouped by UNC5B-low versus UNC5B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC5B→partner) and Y-score (partner→UNC5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Anterior/posterior axon guidance →	+1.318	+2.094	<.001	<.001	3	15
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.074	+2.083	<.001	<.001	3	9
CNS	Response to endoplasmic reticulum stress →	+0.058	+1.497	<.001	.001	2	10
URINARY_TRACT	Thymidine biosynthetic process →	-0.136	-2.425	<.001	<.001	3	8
URINARY_TRACT	2'-deoxyribonucleoside biosynthetic process →	-0.136	-2.425	<.001	<.001	3	8
URINARY_TRACT	Pyrimidine deoxyribonucleoside biosynthetic process →	-0.136	-2.425	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,586 associations by consensus.

Anterior/posterior axon guidance by UNC5B expression — OESOPHAGUS

Explore this box plot interactively →