UNC119

Across TCGA pan-cancer cohorts, UNC119 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UNC119 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher UNC119 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UNC119 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, CCRCC, and GBM are the cancer types where UNC119 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	1.000	0.620	.011	16	view →
CCRCC	DFS	Tertile	III,IV	0.198	0.887	.024	6	view →
GBM	OS	Median	All	0.439	0.597	.029	5	view →
OV	DFS	Median	All	0.897	1.000	.034	4	view →
LSCC	DFS	Median	III,IV	0.446	0.895	.017	4	view →
PDAC	OS	Tertile	II,III,IV	0.964	0.626	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UNC119–UCEC (OS)

Open the UCEC breakdown →