UMPS

Across TCGA cell cohorts, UMPS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,778 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UMPS-associated GO terms across cancer lineages are Pyrimidine nucleoside diphosphate biosynthetic process, Replication fork processing, and UDP biosynthetic process. Each is linked with UMPS in more than 17 cancer types. Because this analysis shows association rather than direction, both UMPS-to-partner and partner-to-UMPS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine nucleoside diphosphate biosynthetic process grouped by UMPS-low versus UMPS-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UMPS→partner) and Y-score (partner→UMPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Pyrimidine nucleoside diphosphate biosynthetic process →	+0.250	+1.153	<.001	.001	3	18
BONE	Replication fork processing →	+0.155	+1.131	<.001	<.001	3	17
OESOPHAGUS	UDP biosynthetic process →	+0.248	+1.233	<.001	<.001	3	17
BONE	DNA replication →	+0.117	+0.888	.001	.001	3	17
SOFT_TISSUE	Double-strand break repair via nonhomologous end joining →	+0.048	+0.922	.001	<.001	3	17
OESOPHAGUS	DNA recombination →	+0.091	+0.964	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,778 associations by consensus.

Pyrimidine nucleoside diphosphate biosynthetic process by UMPS expression — OESOPHAGUS

Explore this box plot interactively →