ULK2

Across TCGA cell cohorts, ULK2 mutation is significantly associated with the RNA expression of many other genes, with 1,352 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ULK2-associated genes across cancer lineages are SI, OR12D3, and CD300H. Each is linked with ULK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ULK2-to-partner and partner-to-ULK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SI grouped by ULK2-low versus ULK2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ULK2→partner) and Y-score (partner→ULK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SI →	+0.013	+4.643	<.001	<.001	3	2
OVARY	OR12D3 →	+0.008	+3.807	<.001	.009	3	2
LARGE_INTESTINE	CD300H →	+0.018	+2.830	<.001	.004	3	2
SOFT_TISSUE	GPR148 →	+0.023	+5.977	<.001	.001	3	1
BLOOD_Lymphoma	PIP →	+0.181	+4.165	<.001	.001	3	1
BLOOD_Lymphoma	CEACAM3 →	+0.078	+3.342	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,352 associations by consensus.

SI by ULK2 expression — BLOOD_Lymphoma

Explore this box plot interactively →