ULK1

Across TCGA patient cohorts, ULK1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,768 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ULK1-associated genes across cancer lineages are IL3RA, RAD51C, and RAB34. Each is linked with ULK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ULK1-to-partner and partner-to-ULK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ULK1 versus IL3RA in HNSC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ULK1→partner) and Y-score (partner→ULK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IL3RA →	-0.604	-0.274	.007	.006	3	3
HNSC	RAD51C →	-0.735	-0.416	<.001	<.001	3	2
GBM	RAB34 →	-0.779	-0.195	.003	.003	3	2
HNSC	CCND3 →	-0.515	-0.273	<.001	<.001	3	2
HNSC	RIMS3 →	+0.890	+0.371	<.001	<.001	3	2
PDAC	E2F8 →	-0.885	-0.648	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,768 associations by consensus.

ULK1 vs IL3RA — HNSC

Explore this scatter interactively →