ULBP3

Across TCGA cell cohorts, ULBP3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,035 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ULBP3-associated genes across cancer lineages are TOP2A, MLPH, and HROB. Each is linked with ULBP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ULBP3-to-partner and partner-to-ULBP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ULBP3 versus TOP2A in BREAST, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ULBP3→partner) and Y-score (partner→ULBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	TOP2A →	+1.452	+1.866	<.001	<.001	3	8
BREAST	MLPH →	-1.966	-0.982	.006	.003	3	6
KIDNEY	HROB →	+1.262	+2.212	.001	.004	2	6
PANCREAS	CDH3 →	+2.476	+1.652	.006	.003	3	5
LUNG_NSCLC_LUAD	TMED3 →	-1.109	-1.333	<.001	<.001	3	5
LUNG_NSCLC_LUAD	PIGP →	-0.845	-1.219	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,035 associations by consensus.

ULBP3 vs TOP2A — BREAST

Explore this scatter interactively →