ULBP2

Across TCGA patient cohorts, ULBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,438 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ULBP2-associated genes across cancer lineages are CTHRC1P1, NDE1, and CLIC3. Each is linked with ULBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ULBP2-to-partner and partner-to-ULBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ULBP2 versus CTHRC1P1 in HNSC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ULBP2→partner) and Y-score (partner→ULBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CTHRC1P1 →	-0.755	-0.645	.002	.002	3	2
LUAD	NDE1 →	+1.112	+1.687	<.001	.009	3	2
BRCA	CLIC3 →	-1.466	-1.618	.003	<.001	3	2
LSCC	TGM5 →	+1.397	+0.830	<.001	<.001	3	2
LSCC	NIPAL2 →	+0.807	+0.936	.002	<.001	3	2
LSCC	PERP →	+1.271	+0.773	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,438 associations by consensus.

ULBP2 vs CTHRC1P1 — HNSC

Explore this scatter interactively →