ULBP1

Across TCGA cell cohorts, ULBP1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ULBP1-associated genes across cancer lineages are TFDP3, C14orf180, and NEXMIF. Each is linked with ULBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ULBP1-to-partner and partner-to-ULBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFDP3 grouped by ULBP1-low versus ULBP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ULBP1→partner) and Y-score (partner→ULBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TFDP3 →	+0.022	+4.518	<.001	<.001	3	1
LARGE_INTESTINE	C14orf180 →	+0.102	+4.155	.002	.003	3	1
LARGE_INTESTINE	NEXMIF →	+0.283	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TFDP3 by ULBP1 expression — LARGE_INTESTINE

Explore this box plot interactively →