UHRF1BP1L

Across TCGA pan-cancer cohorts, UHRF1BP1L mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UHRF1BP1L data layer compared with 24 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UHRF1BP1L mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UHRF1BP1L expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and CCRCC are the cancer types where UHRF1BP1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.963	0.687	.002	35	view →
LSCC	OS	Median	III,IV	1.000	0.735	.003	19	view →
CCRCC	OS	Median	All	0.743	0.921	.002	17	view →
HNSC	DFS	Median	All	0.325	0.875	.010	17	view →
PDAC	OS	Median	II,III,IV	0.512	0.247	.004	5	view →
GBM	OS	Tertile	All	0.246	0.630	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UHRF1BP1L–LUAD (DFS)

Open the LUAD breakdown →