UHRF1BP1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UHRF1BP1L mutation is significantly associated with the RNA expression of many other genes, with 4,165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UHRF1BP1L-associated genes across cancer lineages are SNRPCP20, KCTD9, and GPI. Each is linked with UHRF1BP1L in more than 2 cancer types. Because this analysis shows association rather than direction, both UHRF1BP1L-to-partner and partner-to-UHRF1BP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPCP20 grouped by UHRF1BP1L-low versus UHRF1BP1L-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UHRF1BP1L→partner) and Y-score (partner→UHRF1BP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADSNRPCP20 →+0.202+2.398.002.00633
UCECKCTD9 →+0.549+2.480<.001<.00133
COADGPI →+0.377+3.713.005<.00133
COADPCCB →+0.624+3.362<.001.00433
LUADOR7E111P →+0.016+4.523<.001.00433
UCECPSMC3IP →+0.500+1.595<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,165 associations by consensus.

SNRPCP20 by UHRF1BP1L expression — COAD

Box plot of SNRPCP20 in UHRF1BP1L-low vs UHRF1BP1L-high samples in COAD.

Explore this box plot interactively →

Exploration