UHRF1BP1L

Across TCGA cell cohorts, UHRF1BP1L mutation is significantly associated with the RNA expression of many other genes, with 411 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UHRF1BP1L-associated genes across cancer lineages are IL9, ACO2, and OR6F1. Each is linked with UHRF1BP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both UHRF1BP1L-to-partner and partner-to-UHRF1BP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL9 grouped by UHRF1BP1L-low versus UHRF1BP1L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UHRF1BP1L→partner) and Y-score (partner→UHRF1BP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IL9 →	+0.111	+4.539	<.001	<.001	3	2
LARGE_INTESTINE	ACO2 →	+0.583	+2.265	<.001	.001	3	2
CNS	OR6F1 →	+0.781	+3.874	<.001	.006	3	1
CNS	DEFB136 →	+0.275	+4.772	<.001	.002	3	1
CNS	UGT2B11 →	+0.028	+3.643	<.001	.007	3	1
CNS	OR14A2 →	+0.694	+3.832	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 411 associations by consensus.

IL9 by UHRF1BP1L expression — BLOOD_Leukemia

Explore this box plot interactively →