UHRF1BP1

Across TCGA pan-cancer cohorts, UHRF1BP1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated UHRF1BP1 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher UHRF1BP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UHRF1BP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, PDAC, and HNSC are the cancer types where UHRF1BP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	1.000	0.311	.001	28	view →
PDAC	OS	Quartile	II,III,IV	0.400	0.656	.002	27	view →
HNSC	DFS	Tertile	IV	0.890	0.444	.003	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

UHRF1BP1–UCEC (OS)

Open the UCEC breakdown →