UHRF1BP1

Across TCGA pan-cancer cohorts, UHRF1BP1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of UHRF1BP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where UHRF1BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UHRF1BP1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where UHRF1BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UHRF1BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.777	<.001	10	view →
COAD	Male	All	+0.591	<.001	10	view →
LIHC	Female	II,III,IV	+1.339	<.001	8	view →
STAD	Male	II,III,IV	+1.112	<.001	8	view →
BLCA	All	All	+0.553	.001	8	view →
KIRP	Female	All	+0.989	.010	6	view →
UCEC	All	II,III,IV	+0.891	.030	6	view →
BRCA	All	II,III,IV	+0.439	<.001	6	view →
CHOL	All	All	+2.182	<.001	5	view →
LUAD	All	All	+0.376	<.001	5	view →
LUSC	All	All	+0.325	.001	4	view →
PRAD	All	All	+0.580	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

UHRF1BP1–HNSC

Open the HNSC breakdown →