UHRF1BP1

Across TCGA patient cohorts, UHRF1BP1 mutation is significantly associated with the RNA expression of many other genes, with 4,346 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UHRF1BP1-associated genes across cancer lineages are RNU6-820P, TNFRSF10B, and PSMB6. Each is linked with UHRF1BP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UHRF1BP1-to-partner and partner-to-UHRF1BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-820P grouped by UHRF1BP1-low versus UHRF1BP1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UHRF1BP1→partner) and Y-score (partner→UHRF1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-820P →	+0.501	+5.259	<.001	.007	3	3
UCEC	TNFRSF10B →	+0.496	+1.780	<.001	.003	3	3
UCEC	PSMB6 →	+0.518	+2.247	<.001	<.001	3	3
UCEC	CCDC25 →	+0.443	+4.010	<.001	<.001	3	3
UCEC	UTP11 →	+0.315	+1.452	.007	.002	3	3
UCEC	YRDC →	+0.374	+2.258	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,346 associations by consensus.

RNU6-820P by UHRF1BP1 expression — BRCA

Explore this box plot interactively →