UHRF1BP1

Across TCGA cell cohorts, UHRF1BP1 mutation is significantly associated with the RNA expression of many other genes, with 267 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UHRF1BP1-associated genes across cancer lineages are TLE7, IFNA21, and OR10A4. Each is linked with UHRF1BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UHRF1BP1-to-partner and partner-to-UHRF1BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TLE7 grouped by UHRF1BP1-low versus UHRF1BP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UHRF1BP1→partner) and Y-score (partner→UHRF1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TLE7 →	+0.021	+3.969	<.001	.009	3	2
LUNG_NSCLC_LUAD	IFNA21 →	+0.042	+3.544	<.001	.009	3	2
LARGE_INTESTINE	OR10A4 →	+0.044	+2.102	<.001	.005	3	2
LARGE_INTESTINE	OR5M11 →	+0.093	+2.817	<.001	<.001	3	2
BLOOD_Leukemia	MSMB →	+0.170	+3.774	.002	.008	3	2
SKIN	MYOCOS →	+0.014	+2.183	.006	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 267 associations by consensus.

TLE7 by UHRF1BP1 expression — BLOOD_Leukemia

Explore this box plot interactively →