UGT8

Across TCGA cell cohorts, UGT8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,073 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UGT8-associated GO terms across cancer lineages are Galactolipid biosynthetic process, Galactosylceramide biosynthetic process, and Galactolipid metabolic process. Each is linked with UGT8 in more than 16 cancer types. Because this analysis shows association rather than direction, both UGT8-to-partner and partner-to-UGT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Galactolipid biosynthetic process grouped by UGT8-low versus UGT8-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT8→partner) and Y-score (partner→UGT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Galactolipid biosynthetic process →	+1.539	+2.134	<.001	<.001	3	17
SKIN	Galactosylceramide biosynthetic process →	+1.539	+2.134	<.001	<.001	3	17
SKIN	Galactolipid metabolic process →	+1.365	+1.808	<.001	<.001	3	10
OESOPHAGUS	Protein localization to paranode region of axon →	+1.438	+2.807	<.001	<.001	2	11
SKIN	Galactosylceramide metabolic process →	+1.272	+1.758	<.001	<.001	3	9
URINARY_TRACT	Paranodal junction assembly →	-0.360	-3.021	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,073 associations by consensus.

Galactolipid biosynthetic process by UGT8 expression — SKIN

Explore this box plot interactively →